Genetic risk for Multiple Sclerosis originated in Pastoralist Steppe populations
- Paper
- Sep 26, 2022
- #Biology
Multiple sclerosis (MS) is a modern neuro-inflammatory and -degenerative disease, which is most prevalent in Northern Europe. Whilst it is known that inherited risk to MS is located...
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Nicholas A. Christakis @NicholasAChristakis
ยท
Sep 27, 2022
Wonderful work & thread showing that co-evolution between pathogens and humans ~2-5,000 years ago likely resulted in divergent ancestry-specific selection on immune genes, which incidentally drove increase in genetic risk for Multiple Sclerosis (upon infection with EBV, usually).