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The Cheating Cell: How Evolution Helps Us Understand and Treat Cancer

  • Book
  • Jan 10, 2017
  • #Biology
Athena Aktipis
@AthenaAktipis
(Author)
www.goodreads.com
Hardcover
4.6/5 29 ratings
Hardcover Kindle Audiobook Paperback
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4.11/5 56 ratings
2 Recommenders
2 Mentions
A fundamental and groundbreaking reassessment of how we view and manage cancer When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution a... Show More

A fundamental and groundbreaking reassessment of how we view and manage cancer

When we think of the forces driving cancer, we don't necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer's evolutionary origins, researchers can come up with more effective, revolutionary treatments.

Athena Aktipis goes back billions of years to explore when unicellular forms became multicellular organisms. Within these bodies of cooperating cells, cheating ones arose, overusing resources and replicating out of control, giving rise to cancer. Aktipis illustrates how evolution has paved the way for cancer's ubiquity, and why it will exist as long as multicellular life does. Even so, she argues, this doesn't mean we should give up on treating cancer--in fact, evolutionary approaches offer new and promising options for the disease's prevention and treatments that aim at long-term management rather than simple eradication. Looking across species--from sponges and cacti to dogs and elephants--we are discovering new mechanisms of tumor suppression and the many ways that multicellular life-forms have evolved to keep cancer under control. By accepting that cancer is a part of our biological past, present, and future--and that we cannot win a war against evolution--treatments can become smarter, more strategic, and more humane.

Unifying the latest research from biology, ecology, medicine, and social science, The Cheating Cell challenges us to rethink cancer's fundamental nature and our relationship to it.

(From Goodreads)

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ISBN: 0691163847

ISBN-13: 9780691163840

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Richard Dawkins @RichardDawkins · Apr 7, 2022
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The Cheating Cell by @AthenaAktipis. Darwinian approach to evolution of cancer and cancer-resistance. Brilliant book, up there with Nesse & Williams. Tussle between opposing selection pressures means cancer is an inevitable byproduct of selection for individual advantage.
Geoffrey Miller @primalpoly · Sep 13, 2022
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Here's a great book (2020) by @AthenaAktipis about the evolutionary origins & nature of cancer. Might help understand the problem & guide research.
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