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Problems with Ferguson et al, owing to scaling and granularity.
2015 •
BMJ (Clinical research ed.)
Poor description of non-pharmacological interventions: Analysis of consecutive sample of randomised trials2013 •
Journal of Clinical Epidemiology
No evidence for intervention-dependent influence of methodological features on treatment effect2013 •
Journal of Clinical Epidemiology
Early detection of the existence or absence of the treatment effect: A cumulative meta-analysis2020 •
World Development
Randomized interventions and “real” treatment effects: A cautionary tale and an example2020 •
2020 •
Informed decision-making is increasingly being adopted by global healthcare policy to improve evidence based treatment decisions yet its uptake into clinical practice has been slow. Whilst current clinical practice guidelines and synthesised products (e.g. systematic reviews, evidence summaries) increase access to evidence of treatment effects, they often fail to provide additional information needed to make a fully informed choice. Moreover, a lack of brevity and the use of research jargon are barriers to their implementation in practice. As well as access to information about the benefits and harms of healthcare interventions, consumers also need additional information such as treatment costs, dosage, and the quality of evidence underpinning treatment effects in order to make informed choices. Currently, there are few examples of clinical practice guidelines or synthesised products that present this additional information in one-place and in a concise manner. Here we present such a method and describe how we developed the Evidence of Effects Page. The Evidence of Effects Page is a unique one-page summary of evidence that presents information not only on treatment effects and harms, but also precision of estimates, the quality of evidence and treatment costs. Our methodology can be applied to create additional Evidence of Effects Pages for treatments and interventions for other medical conditions as required. Compared with current products, the Evidence of Effects Page provides additional information for making decisions about healthcare treatments and has potential to facilitate greater adoption of informed decision-making and patient centered care in clinical practice.
Health Services Research
Assessing Heterogeneity of Treatment Effects: Are Authors Misinterpreting Their Results?2010 •
Journal of Clinical Epidemiology
Cherry-picking by trialists and meta-analysts can drive conclusions about intervention efficacy2017 •
Research on Social Work Practice
25 Years of Complex Intervention Trials2017 •
For the past 25 years, I have led multiple group-randomized trials, each focused on a specific underserved population of youth and each one evaluated health effects of complex interventions designed to prevent high-risk behaviors. I share my reflections on issues of intervention and research design, as well as how research results fostered my evolution toward addressing fundamental social determinants of health and well-being. Reflections related to intervention design emphasize the importance of careful consideration of theory of causes and theory of change, theoretical comprehensiveness versus fundamental determinants of population health, how high to reach, and health in all policies. Flowing from these intervention design issues are reflections on implications for research design, including the importance of matching the unit of intervention to the unit of assignment, the emerging field of public health law research, and consideration of design options and design elements beyond...
2018 •
arXiv: Solar and Stellar Astrophysics
Signs of atmospheric inhomogeneities in cool stars from 1D-NLTE analysis of iron lines2013 •
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
Möglichkeiten und Grenzen der transkraniellen Farbduplexsonographie bei der Darstellung intrakranieller arteriovenöser Malformationen2006 •
Credit and Capital Markets – Kredit und Kapital
Ein Drei-Punkte-Plan zur Reform der Geldpolitik2013 •
2013 •
Jurnal Penyuluhan
Adoption of Fisheries Diversification Innovation in Poklahsar in Cigasong Sub-District, Majalengka District2020 •
2016 •
2021 •
The International Journal of Business & Management
In Selected Commercial Effect of Employee Commitment and Organization Performance Banks in Uasin Gishu County, Eldoret, Kenya2020 •
European Journal of Anaesthesiology
Diastolic dysfunction in patients with preserved systolic function undergoing cardiac surgery: is there a role for BNP in preoperative diagnosis?2007 •
Journal of Environmental Engineering
Effect of Quality Electrolyte Fluid on Removing MTBE from a Clay Soil Using Electrokinetic Technique2018 •
1991 •
Digestive Surgery
Survey Results of the Expert Meeting on Laparoscopic Surgery for Gallbladder Cancer and a Review of Relevant Literature2018 •
2021 •
2014 •
American Journal of Physiology-Heart and Circulatory Physiology
Chronic inhibition of phosphodiesterase 5 with tadalafil attenuates mitochondrial dysfunction in type 2 diabetic hearts: potential role of NO/SIRT1/PGC-1α signaling2014 •